NATURAL HOME CURES · NOPAL SCIENCE

Methionine
& Nopal

An essential amino acid linking proteins, sulfur and the chemistry of our cells.

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Methionine and its roles in cellsMethionine is a sulfur-containing amino acid used in proteins and, through several steps, in the production of cysteine and SAM.SSULFUR-CONTAINING AMINO ACIDMethionineProteinsCysteineSAMSimplified connections through several biological steps
PROTEINS · SULFUR · CELL CHEMISTRYOne building block.
Several roles in your cells.

Methionine is one of the building blocks your body uses to make proteins. It also supplies sulfur for other compounds your cells need.(1)

Methionine is an essential amino acid. This means the body cannot make it on its own, so we need to obtain methionine from the foods we eat.(2)

What Does Methionine Do?

A SIMPLIFIED CONNECTION

Methionine → Cysteine → Glutathione

Several regulated steps connect these substances. More methionine does not automatically mean more glutathione.

Your body can use methionine to make cysteine, another sulfur-containing amino acid. This conversion involves several carefully controlled steps.(3)

Cysteine is one of the building blocks used to make glutathione, a substance that helps protect cells against oxidative stress.(4)

The body regulates this pathway, so eating more methionine does not automatically produce more glutathione.

Methionine and the Body’s "Chemical Tags"

METHYL-GROUP TRANSFERS

Methionine → SAM

S-adenosylmethionine donates small methyl groups in normal processes involving DNA, proteins and other molecules.

Your body can turn methionine into S-adenosylmethionine, usually shortened to SAM.(5)

SAM transfers small chemical groups, called methyl groups, to other molecules. Think of these as tiny chemical tags.

These transfers take part in normal processes involving DNA, proteins and other substances inside your cells.(5), (6)

Where Does Methionine Come From?

Methionine occurs naturally in many protein-containing foods, including:

  • Roasted chicken
    Meat and poultry
  • A serving of fish
    Fish
  • Eggs
    Eggs
  • Milk and dairy foods
    Milk and dairy products
  • Lentils and chickpeas
    Beans, lentils and soy foods
  • Nuts and seeds
    Nuts and seeds
  • Whole grains
    Whole grains
  • Leafy green vegetables
    Leafy vegetables
  • Cleaned Nopal cactus pads and sliced nopales
    Nopal cactus pads

How Much Methionine Is in Nopal?

Fresh Nopal pads and prepared nopales
NATURALLY OCCURRING METHIONINE · RAW NOPALESAbout 15 mgper 100 g of raw edible cactus pads

USDA FoodData Central · “Nopales, raw”

The USDA entry lists 0.015 grams of methionine per 100 grams of raw nopales, equal to 15 milligrams. This provides context for the amount in fresh cactus pads.(9)

Researchers have identified methionine among the naturally occurring amino acids in Nopal cactus.(7)

Nopal also contains fiber, vitamins, minerals, pigments and other plant compounds.(7), (8)

These findings describe the plant’s composition. They do not establish the methionine amount in a serving of our finished products.

From Our Farms to Your Bottle

Botanical illustration of Nopal cactus

Our Nopal capsule story begins on our mountain farms in Mexico, where Opuntia streptacantha grows at about 8,200 feet in rich volcanic soil. Sunlight, temperature, and rainfall shape the living cactus.

We stay involved from growing through harvest and preparation of the capsules. This growing environment is part of the story behind each amino acid discussed here.

More Than Methionine

Methionine is one part of Nopal’s wider nutritional picture. Explore the other science articles to learn about the cactus’s fiber, vitamins, minerals and other plant compounds.

Natural Home Cures products from left to right: Nopal cactus capsules, prickly pear drops, and Nopal cactus powder

FROM CACTUS TO PRODUCT

Meet Our Nopal Cactus & Prickly Pear Family

Nopal cactus capsules, prickly pear drops, and Nopal cactus powder.

Explore Nopal Cactus →
The research behind this article

Source References

9 sources Show referencesHide references
  1. 01
    Nutrition referencePhysiology, Proteins.

    LaPelusa A, Kaushik R. StatPearls. National Center for Biotechnology Information.

    Full citation
    LaPelusa A, Kaushik R. “Physiology, Proteins.” StatPearls. National Center for Biotechnology Information.
    View source
  2. 02
    Research referenceNational Academies of Sciences, Engineering, and Medicine. Dietary Reference Intakes: The Essential Guide to Nutrient Requirements. National Academies Press.
    Full citation
    National Academies of Sciences, Engineering, and Medicine. Dietary Reference Intakes: The Essential Guide to Nutrient Requirements. National Academies Press.
    View source
  3. 03
    Research referenceSulfur Amino Acid Metabolism: Pathways for Production and Removal of Homocysteine and Cysteine.

    Stipanuk MH. Annual Review of Nutrition. 2004;24:539–577.

    Full citation
    Stipanuk MH. “Sulfur Amino Acid Metabolism: Pathways for Production and Removal of Homocysteine and Cysteine.” Annual Review of Nutrition. 2004;24:539–577.
    View source
  4. 04
    Research referenceGlutathione Synthesis.

    Lu SC. Biochimica et Biophysica Acta. 2013;1830(5):3143–3153.

    Full citation
    Lu SC. “Glutathione Synthesis.” Biochimica et Biophysica Acta. 2013;1830(5):3143–3153.
    View source
  5. 05
    Research referenceMethionine Metabolism and Liver Disease.

    Mato JM, Martínez-Chantar ML, Lu SC. Annual Review of Nutrition. 2008;28:273–293.

    Full citation
    Mato JM, Martínez-Chantar ML, Lu SC. “Methionine Metabolism and Liver Disease.” Annual Review of Nutrition. 2008;28:273–293.
    View source
  6. 06
    Research referenceThe Sulfur-Containing Amino Acids: An Overview.

    Brosnan JT, Brosnan ME. Journal of Nutrition. 2006;136(6 Suppl):1636S–1640S.

    Full citation
    Brosnan JT, Brosnan ME. “The Sulfur-Containing Amino Acids: An Overview.” Journal of Nutrition. 2006;136(6 Suppl):1636S–1640S.
    View source
  7. 07
    Research referenceNopal Cactus (Opuntia ficus-indica) as a Source of Bioactive Compounds for Nutrition, Health and Disease.

    El-Mostafa K, El Kharrassi Y, Badreddine A, et al. Molecules. 2014;19(9):14879–14901.

    Full citation
    El-Mostafa K, El Kharrassi Y, Badreddine A, et al. “Nopal Cactus (Opuntia ficus-indica) as a Source of Bioactive Compounds for Nutrition, Health and Disease.” Molecules. 2014;19(9):14879–14901.
    View source
  8. 08
    Research referenceCactus Stems (Opuntia spp.): A Review on Their Chemistry, Technology, and Uses.

    Stintzing FC, Carle R. Molecular Nutrition & Food Research. 2005;49(2):175–194.

    Full citation
    Stintzing FC, Carle R. “Cactus Stems (Opuntia spp.): A Review on Their Chemistry, Technology, and Uses.” Molecular Nutrition & Food Research. 2005;49(2):175–194.
    View source
  9. 09
    USDA food composition referenceNopales, raw.

    U.S. Department of Agriculture, Agricultural Research Service. FoodData Central. FDC ID 168571; SR Legacy, NDB 11963.

    Full citation
    U.S. Department of Agriculture. FoodData Central. “Nopales, raw.” FDC ID 168571; SR Legacy. Methionine: 0.015 g per 100 g of raw edible food, equivalent to 15 mg. General raw-food composition; not a finished-product assay.
    View source